MARC – Manipal Assisted Reproduction Centre

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offers a wide range of treatment programs for subfertile couples seeking assisted conception.

The Doctors and scientists doing the treatment have undergone specialized training abroad and have been working with subfertility problems since 1990. The pioneering technological improvements make MARC one of the most advanced centres for the treatment of infertility in India. The centre has a fully equipped andrology laboratory for male subfertility evaluation and semen banking for short term and long term storage. Embryology laboratory with all modern facilities including micromanipulation, which is offered by a very few centres in India.

MARC offers options during evaluation and treatment. Testing procedures to determine male partner status, uterine/ovarian status and tubal status help to recommend treatment options for the couples. Many patients attempt a less invasive treatment plan at first such as Intra Uterine Insemination (IUI). If after several (usually 3-6) cycles the treatment does not result in pregnancy, the patient then moves to a more complex treatment such as IVF or ICSI. Facilities for cornual recannalisation by Fluroscopic control and Hysteroscopic cannulations are available. MARC also pursue research programs for improving the quality of management of subfertile couples. Research work on animals is also being  carried out and this is one of the first IVF centre in the country associated with a university medical college

Services Offered

  1. Induction of Ovulation
  2. Laparoscopic procedures
  3. Transvaginal Sonographic Procedures
  4. Cornual Recannalisation
  5. Intra Uterine Insemination (husband/donor)
  6. In Vitro Fertilization (IVF)
  7. Intra Cytoplasmic Sperm Injection (ICSI)
  8. Vasal, Epididymal and Testicular Sperm Extraction (MESA/TESA)
  9. Egg/Embryo Donation Program
  10. Embryo and Semen Banking
  11. Comprehensive Male Infertility Evaluation and Treatment
  12. Male Reproductive Laboratory.

Depending upon the diagnosis, treatment may include timing of insemination procedures, hormone therapy to correct abnormalities in the natural menstrual cycle, Intra Uterine Insemination (IUI) to bypass problems with sperm/cervical mucus interactions, In Vitro Fertilization (IVF-ET) with Embryo Transfer, Gamete intra fallopian transfer (GIFT) or Micromanipulation (ICSI).

Brief description about Assisted Reproductive Techniques:

IUI is a simple and less invasive technique in which the husband or donor sperm is placed in the womb using a catheter. IUI is indicated for the treatment of low sperm count or unexplained infertility. Using appropriate laboratory technique, the sperm can be separated from the seminal fluid and resuspended in a very small volume of sterile medium which will keep the sperm alive and actively motile.

IVF is a procedure that involves retrieving the eggs from the wife after sufficient medication to stimulate the ovaries to develop as many follicles. The eggs are fertilized in the dish using husband’s sperm. Fertilized eggs are then transferred after 2 days into the womb where implantation and embryo development  occur, as in a normal pregnancy.

Donor eggs and donor sperm: For women experiencing failure of their ovarian function and women over age 40 with poor quality eggs, the use of donated eggs from their sister or another female may be the best option to achieve conception. The semen bank provides donor sperm for use in IUI and IVF when the husband has no sperm or if he has genetic disorders.

ICSI or Intra Cytoplasmic Sperm Injection is used to treat couples who previously had failure in achieving conception due to the male partner’s extremely low number of normal sperm. ICSI has revolutionized’ treatment for severe male factor infertility because the procedure requires only one healthy sperm per egg to achieve fertilization. When there is an absence of sperm in the semen, surgically sperm can be removed from the testis (TESA) or from epididymis (MESA).

Dr. Pratap Kumar
Professor and Head Department of Obstetrics and gynecology
Kasturba Medical College, Manipal – 576 119
Karnataka, India
E-mail: drpratapkumar@hotmail.com

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